Molecular Biology

Harnessing the Power of NGS and PCR to Decode Genetic Mysteries for Personalised Care

Committed to precision and innovation, we employ cutting-edge molecular technologies to decode the genetic makeup of individuals, offering insights into disease risk, prognosis, and facilitating personalised treatment strategies.

Find Your Package Book an Appointment

Key Features

1. Comprehensive Reproductive Genetic Profiling:

Our Molecular Biology division specialises in comprehensive genetic profiling, analysing DNA, RNA, and other molecular markers to uncover genetic variations associated with various diseases.
From hereditary conditions to somatic mutations, our analyses provide a profound understanding of individual genetic landscapes.
Noninvasive Prenatal Testing (NIPT) – screens all chromosomal aneuploidies as well as microdeletions as recommended by American College of Medical Genetics and Genomics (ACMG).
Preimplantation Genetic Test Aneuploidy (PGT-A) and Product of Conception (PoC) – screens embryos for extra or missing chromosomes (aneuploidy) increasing successful pregnancy outcomes. Embryos with correct number of chromosomes result in successful IVF and a healthy pregnancy.
Endometrial Receptor Analysis (ERA) – provides information on the window of implantation for successful transplantation, by analysing endometrial tissue for gene expression related to endometrial receptivity using ML technology.
Endometrial Microbiome Analysis (EMA) – provides quantitative information on pathogenic as well as healthy microbiomes at strain level by analysing endometrial microbiomes for bacteria, virus, fungi and parasites using whole genome metagenomics sequencing and ML technology.

2. Infectious Disease Risk Assessment:

Genetic risk assessments enable the identification of predispositions to various diseases, empowering individuals, and healthcare providers with information for proactive health management.
We focus on actionable genetic insights that guide preventive measures and early interventions by conducting following tests –
Infectious Disease One (ID-1) – detects and quantifies more than 5000 pathogens (bacteria, fungi, virus, parasite and antibiotic resistance genes). Hypothesis free testing for any infectious disease (respiratory tract infection, CNS infection, gastrointestinal tract infection, UTI, orthopaedic implant related infection, fever, hepatitis or sepsis). Works with any clinical sample be it plasma, CSF, bronchoalveolar lavage, sputum, nasopharyngeal swab, tracheal aspirate, ocular swab, stool, urine, synovial fluid or lymph node biopsies and tissues.
Infectious Disease Two (ID-2) – detects more than 2000 pathogens (bacteria, fungi, virus, parasite, and antibiotic resistance genes)

Syndromic Panels

TB-1 is based on targeted NGS and can identify all species of mycobacteria in pulmonary and extra pulmonary cases. Works on all clinical samples and tests for detection and resistance profiling of mycobacterium tuberculosis.

Other syndromic panels include :-

Pneumonia NGS Panel
Meningitis/Encephalitis NGS Panel
Sepsis Panel
Endometritis NGS Panel
Gastroenteritis NGS Panel
UTI NGS Panel

Specialised Molecular Services:

Genetic Counselling:

Our genetic counsellors collaborate with individuals and healthcare providers to interpret genetic results, offering guidance on potential health implications and family planning.
Genetic counselling ensures that individuals make informed decisions based on their genetic information.

Cancer Genomics:

Molecular profiling in oncology extends to cancer genomics, allowing for the identification of specific genetic mutations driving tumour growth.
This information guides oncologists in selecting targeted therapies for personalised cancer treatment plans.

Cutting-Edge Technologies:

Next-Generation Sequencing (NGS):

Our facility harnesses the power of NGS for high-throughput genomic analysis, enabling the identification of genetic variations with unparalleled accuracy.
NGS facilitates a comprehensive understanding of genetic landscapes, contributing to advancements in precision medicine.

Polymerase Chain Reaction (PCR):

PCR technology is employed for the amplification of specific DNA sequences, enabling the detection of genetic mutations with exceptional sensitivity.
This technology plays a crucial role in molecular diagnostics, especially in identifying rare genetic variants.

Patient-Centric Approach:

Rapid Genetic Insights:

Recognising the significance of timely genetic information, our Molecular Biology department ensures swift processing.
Timely reporting empowers individuals and healthcare providers with the information needed for proactive health management

Tailored Treatment Plans:

Collaborating with healthcare providers, our team contributes to the development of tailored treatment plans based on individual genetic profiles.
This personalised approach ensures that treatment strategies align with the unique genetic makeup of each patient.

Innovation and Research:

Research in Genomic Medicine:

Actively engaged in research initiatives, we contribute to the field of genomic medicine, exploring novel biomarkers and genetic associations with diseases.
Our commitment to ongoing research positions us at the forefront of molecular biology advancements.

Continuous Professional Development:

Our molecular biologists participate in continuous professional development, staying abreast of the latest molecular technologies and genetic research.
This dedication ensures that our Molecular Biology department remains a centre of excellence in genetic diagnostics.

Related Services

Microbiology

Our Microbiology vertical is dedicated to comprehensive microbial analysis, providing accurate insights into infectious agents, antibiotic resistance patterns, and contributing to targeted antimicrobial therapy for effective disease management.

Histopathology & Cytopathology including IHC

We specialise in unraveling the mysteries of tissues and cells, employing advanced techniques such as Immunohistochemistry (IHC) to provide unparalleled diagnostic insights for personalised patient care.

Haematology

Our Haematology department stands at the forefront of diagnostic excellence, offering a comprehensive range of advanced tests and analyses aimed at unraveling the intricacies of bloodrelated disorders.